This is a prehistoric method staggering innovation
If you can’t measure it, you can’t improve it. Our technology allows medical professionals to treat each patient encounter like a study visit.
Through our Multichannel High-Resolution Data Capture, we collect patient-reported outcomes and translate them into a common measurement language. We are marrying the subjective (PROs) with the objective (HRV, EEG, and urine biomarkers) to make pain a data-driven disease.
Come talk to us about the billion dollar opportunity to make pain a data driven disease.
Ethos Labs Foundation Pain Index (FPI) has developed a composite score comprised of a panel of eleven functional pain biomarkers, which is based on the abnormal biochemistry described in a population study of over 17,000 patients on opioids for chronic pain. The Celeri Health Real World Outcomes platform was used to cross-validate these results with PROs to better understand the daily lives of individuals with chronic pain in the context of their biomarker profiles. The result of the analysis detailing the corroboration between the FPI and PROMIS-29 in real-world patients noted significant associations with multiple domains, including physical function, pain impact score, fatigue, pain interference, and depression. This validates the utility of the FPI for identifying the composite chronic pain state. Continued research is underway to calibrate this approach so as to define next step in clinical decision making.
Celéri Health is being used to study objective measures for changes in pain sensitivity. Due to limited tools to objectively quantify pain clinically, clinicians rely on patient reported scales to determine pain treatment options (e.g.,opioid dosage is typically to the patient’s estimate of pain). Without an objective test of pain sensitivity, a kind of “blood pressure” equivalent to pain, treatment decisions rely on patient’s claims of pain, which may be based on the patient’s desire for treatments due to addiction or anxiety about pain that they experience as intolerable. Patient’s know that if they report more pain, it is likely that their physician will prescribe more pain medication. For this reason, objective tests for pain sensitivity are needed to assess patient’s complaints with precision.
The Celéri Health platform is being used in conjunction with the Muse S (choosemuse.com) biofeedback training device to assess impact on quality of life using PROs, bio-signals (EEG, HRV, Cerebral SpO2), and pain tolerance and sensitivity using a cold pressor test. This multichannel data capture study will allow us to objectively correlate bio-signals of pain with the patient’s mood, sleep, and function is currently underway. Further information can be found here at Clinicaltrials.gov.
As a patient living with chronic pain, it was frustratingly inadequate to communicate the challenges we face in everyday life on a 0-10 scale. As a Celéri Health patient, my clinician starts each visit by measuring what matters in pain care. Each chronic pain experience is multidimensionally assessed with the PROMIS-29 profile to quantify individualized impacts on mood, sleep, function, social participation, and pain interference with daily activities. Reviewing these longitudinal assessments at the beginning of each visit serves as a compass for care, and helps my medical team focus on meaningful goals for care.
At Celéri Health we understand that not all patients are the same. Our co-founders Dr. Michael Fishman was recently interviewed alongside one of his patients. Listening to the chronic pain journey and impact of treatment on quality of life is a driving force behind what we do at Celéri Health.
Physical Health | Mental Health | Social Health | |
---|---|---|---|
PROMIS
Profile Domains |
Fatigue
Pain Intensity Pain Interference Physical Function Sleep Disturbance |
Anxiety
Depression |
Ability to Participate in Social Roles & Activities |
PROMIS
Additional Domains |
Dyspnea
Gastrointerstinal Symptoms Itch Pain Behavior Pain Quality Pain Function Sexual Function Sleep-related Impairment |
Alcohol
Anger Congnitive Function Life Satisfaction Meaning & Purpose Positive Affect Psychosocial Illness Impact Self-efficacy for Managing Chronic Conditions Smoking Substance Use |
Companionship
Satisfaction with Social Roles & Activities Social Isolation Social Support |
Sean is currently the Managing Partner of SHP, LLC Advising Innovative clients in healthcare, health-tech and provider companies on matters of strategic importance at the board and c-suite levels. He is a seasoned operational executive in both public and private environment. That operational experience has been coupled with a deep transactional track record of accomplishment across verticals.
Among those experiences are founding companies and / or advising companies in Heath-data, Health-tech, Behavioral Health, PMR, Oncology, Specialty group practice and Revenue Cycle. Of note is Firstlight Intelligence a company Sean built through innovative technology and resourcing to construct the first intricate real time landscape of the entire US healthcare provider market which later became the “data backbone” of several health data companies.
Prior to SHP Sean served as VP Corporate Development for Foster Management a PE fund investing throughout the healthcare industry and in allied support services. Sean built through acquisition some of the more successful companies that “went public” during his tenure. This experience was buttressed by several years as a med-surg and behavioral hospital administrator focusing on building alternate care delivery systems.
Dr. Fishman is a practicing pain specialist in the Philadelphia area with a diverse clinical practice that includes innovation, clinical research, and the evidence-based treatment of painful conditions. At Celéri Health, Dr. Fishman is committed to redefining the outcomes metrics we use to measure response to pain care and neuromodulation through the clinical development of the Real World Outcomes platform. Dr. Fishman received his undergraduate degree at Franklin & Marshall College, his medical degree at Jefferson Medical College and a Masters of Business Administration at Drexel University’s LeBow College of Business. He also completed his internship at Lankenau Hospital, residency in anesthesiology at Yale University, and pain medicine fellowship at Stanford University. He is on the Board of Directors of the North American Neuromodulation Society and is a key opinion leader in the field of neuromodulation and interventional pain care, frequently publishing and presenting his work on national and international podiums.
Dr Pope is the President & CEO of Evolve Restorative Center in Northern California. He is the President of the California Society of Interventional Pain Physicians and serves the North American Neuromodulation Society (NANS) as an ex-officio director at large for the International Neuromodulation Society, is the co-chair for the CME committee, the co-chair for the pre-conference training workshop in the biennial meeting in Sydney, Australia, and the co-chair for the Young Neuromodulation Committee. He also is the co-founder of the Special Interest Group in Neuromodulation for the American Society of Regional Anesthesia (ASRA). Dr Pope has published over 100 peer-reviewed articles while working with medical device start up companies and established industry partners to provide strategic planning and execution for patient-centric adoption and supportive patient outcomes.
David has more than a decade of experience leading and managing successful technology companies. David was the Founder & CTO of Loan Ecosystem Online. Prior to founding Loan Ecosystem Online, David was CTO of PulsePoint and BlueCava which were acquired by WebMD and Qualia respectively. David was the Chief Technology Officer of LiftDNA, a leading SSP (sell-side platform), before it was acquired by OpenX in February 2012. Prior to LiftDNA, David served as the Chief Architect of mOcean, the industry leading solution to mobile ad serving which was acquired by Pubmatic.
David began his career as a Systems Engineer at Sun Microsystems and was later recruited by TimeSys as one of its first employees to work on Real Time Linux and Java. David graduated with a degree in Computer Science Engineering from the University of Pennsylvania.
Carol was a founding partner and Executive Vice President of The Higgins Group, one of the top executive search firms in the life science industry. Over her 20 year career in executive search, Carol gained a reputation for her insights, integrity and an ability to build and retain strong teams. She successfully coached many executives on how to bring out the best in themselves and their teams. Previously, Carol was a co-founder & commercial officer in a software start up based in Philadelphia. Carol earned a Bachelor of Science degree with Honors from University of Maryland.
John has extensive experience in corporate finance, executive leadership, and private equity. He has held operating roles at Target RWE, Dodge Data & Analytics, and IMS Health (now IQVIA). John co-led the middle-market investment team at DW Partners and was a member of the investment teams at Versa Capital Partners and Cerberus Partners. John began his career as a Project Engineer at the ECRI Institute, a healthcare consultancy and think tank. He graduated from the University of Pennsylvania with a BSE in Bioengineering and received an MBA with Honors, Beta Gamma Sigma, from Temple University. He also holds an MA in Theology from Villanova University where he is an adjunct professor in the Theology Department.
Chris graduated with a BS in Finance & Operations Management from the University of Delaware and subsequently spent 6 years working on JP Morgan’s US Treasury Desk as a trading assistant. Chris traded NYC for Chapel Hill where he received is MBA from University of North Carolina with a concentration in Entrepreneurship. Upon graduation and prior to joining Celéri Health, Chris was drawn to the world of entrepreneurship and found himself working for a digital start-up based in Cape Town, South Africa helping develop market entry strategy and leading US Operations.
Jean is a Clinical Research Professional with over 20 years experience leading global clinical studies in both the CRO and pharmaceutical industries. Her clinical trial management expertise spans Phase I-IV studies across multiple therapeutic areas. Jean is committed to leveraging Patient Reported Outcomes and Real World Data from Electronic Health Records to enhance a product’s value story and ensure smart decisions are made for the treatment of pain through analysis of real-world evidence and the patient experience.
David graduated with a BA in Biology from Franklin & Marshall College. Prior to joining Celéri, he worked as a clinical research intern at a pain management clinic in Lancaster, PA and as a care manager at a charity clinic in Gainesville Georgia. David has a passion for improving healthcare access for patients who need it most.
Lindsay Kate graduated from Franklin and Marshall with a BA in Biological Foundations of Behavior, Neuroscience. Prior to joining Celéri Health she spent two years working as a Clinical Research Coordinator and medical assistant at a pain management practice in the Philadelphia area. Lindsay Kate has an interest in Neuromodulation and the role Real World Outcomes plays in personalizing Neuromodulation treatments.